Crystal structure of Pla l 1 reveals both structural similarity and allergenic divergence within the Ole e 1–like protein family
Teresa Stemeseder & Regina Freier & Sabrina Wildner, Julian E. Fuchs, Peter Briza, Roland Lang, Eva Batanero, Jonas Lidholm, Klaus R. Liedl, Paloma Campo, Thomas Hawranek, Mayte Villalba, Hans Brandstetter, Fatima Ferreira, Gabriele Gadermaier
Abstract:
Knowledge of structural and immunological features of allergens is important for understanding IgE sensitization and disease eliciting mechanisms of allergenic molecules. Despite the fact that Ole e 1–like proteins are driving type I allergies within several pollen sources,1,2 there is currently no information regarding their tertiary structure. Ole e 1–like proteins are characterized by 3 conserved disulfide bonds and the [EQT]-G-X-V-Y-C-D-[TNP]-C-R consensus pattern while their biological function is unknown.
The open access article can be found  here.

Reviewed by Chiara Cabrele