Risch neu

Head of Research Group

Univ.-Prof. Dr. BA. MA. Angela Risch
Deputy Head of Department, Head of Research Group

Hellbrunner Strasse 34, Room D-3.017A, 5020 Salzburg

Tel.: +43 (0) 662 / 8044 -7220
E-Mail:

Senior Scientist

Dipl.Biol.-Dr. Florian Wolff
Senior scientist

Hellbrunner Strasse 34, 5020 Salzburg

Tel.: +43 (0) 662 / 8044-7221
E-Mail:

POSTDOC

Ing. Dr.rer.nat. Angelika Lahnsteiner, MSc B.rer.nat.
University Assistent – tenured Postdoc, Deputy Study Program Chair for Molecular Biology, Project Leader: EpiDrive – DNA secondary structures under control of DNA methylation

Hellbrunner Strasse 34, 5020 Salzburg

Tel.: +43 (0) 662 / 8044-7223
E-Mail:

Research Interests:
I am interested in the intricate interplay between DNA secondary structures, such as G-quadruplexes and R-loops, and DNA methylation. My research focuses on elucidating how these structural elements influence methylation patterns and how these patterns are altered in various diseases. Furthermore, we seek for new methods in detecting these structural elements, why we developed together with Prof. Makova PDAL-Seq ( https://pubmed.ncbi.nlm.nih.gov/38521584/). Of particular interest is the investigation of whether differential methylation and G-quadruplex formation sites are present early in disease progression, especially in metabolic diseases, potentially even before the onset of cancer. This exploration could unveil critical biomarkers and therapeutic targets for early disease detection and intervention.

Collaboration partners on DNA secondary structures
– Prof. Kateryna Makova, Eberly College of Science at the Pennsylvania State University, USA – http://www.bx.psu.edu/makova_lab/#hero_carousel
– Dr. Matthias Weissensteiner, Institute of Avian Research, Germany – https://scholar.google.se/citations?user=g3EcMLMAAAAJ&hl=de