Selected Publications

• Quantitative and functional characterisation of extracellular vesicles afterpassive loading with hydrophobic or cholesterol-tagged small molecules. Tréton G., Sayer C., Schürz M., Jaritsch M., Müller A., Matea C.T., Stanojlovic V., Melo-Benirschke H., Be C., Krembel C, Rodde S., Haffke M., Hintermann S., Marzinzik A., Ripoche S, Blöchl C., Hollerweger J., Auer D., Cabrele C., Huber C.G., Hintersteiner M., Wagner T, Lingel A,*, Meisner-Kober N. Journal of Controlled Release 361 (2023) 694–716
• Surface display of functional moieties on extracellular vesicles using lipid anchors. Zheng W, Schürz M, Wiklander RJ, Gustafsson O, Gupta D, Slovak R, Traista A, Coluzzi A, Roudi S, Barone A, Farcas D, Kyriakopoulou E, Galli V, Sharma H, Meisner-Kober N,  Honcharenko M, Andaloussi SEL. Journal of Controlled Release 357 (2023) 630–640
• EVAnalyzer: High content imaging for rigorous characterisation of single extracellular vesicles using standard laboratory equipment and a new open-source ImageJ/Fiji plugin. Schürz M, Danmayr J, Jaritsch M, Klinglmayr, Melo Benirschke H, Matea CT, Zimmerebner P, Rauter J, Wolf M, Gueths Gomes F, Kratochvil Z, Heger Z, Miller A, Heuser T, Stanojlovic V, Kiefer J, Plank T, Johnson L, Himly M, Blöchl C, G. Huber C, Hintersteiner M, Meisner-Kober N. J ExtracellVesicles. 2022 Nov; 11:12282 doi: 10.1002/jev2.12282
• Systematic characterization of extracellular vesicle sorting domains and quantification at the single molecule – single vesicle level by fluorescence correlation spectroscopy and single particle imaging. Corso G, Heusermann W, Trojer D, Görgens A, Steib E, Voshol J, Graff A, Genoud C, Lee Y, Hean J, Nordin JZ, Wiklander OPB, El Andaloussi S, Meisner-Kober N. J Extracell Vesicles. 2019 Sep 18;8(1):1663043. doi: 10.1080/20013078.2019.1663043. eCollection 2019. PMID:   31579435

• Molecular basis for AU-rich element recognition and dimerization by the HuR C-terminal RRM. Ripin N, Boudet J, Duszczyk MM, Hinniger A, Faller M, Krepl M, Gadi A, Schneider RJ, Šponer J, Meisner-Kober NC, Allain FH. Proc Natl Acad Sci U S A. 2019 Feb 19;116(8):2935-2944. doi: 10.1073/pnas.1808696116.

• Structural basis of siRNA recognition by TRBP double-stranded RNA binding domains. Masliah G, Maris C, König S, Yulikov M, Aeschimann F, Malinowska AL, Mabille J, Weiler J, Holla A, Hunziker J, Meisner-Kober N, Schuler S, Jeschke G, Allain F.  EMBO Journal, 2018, EMBO J. 2018 Mar 15;37(6). pii: e97089. doi: 10.15252/embj.201797089.

• Exosomes surf on filopodia to enter cells at endocytic hot spots, traffic within endosomes, and are targeted to the ER. Heusermann W, Hean J, Trojer D, Steib E, vonBueren S, Graff-Meyer A, Genoud C, Martin K, Pizzato N, Voshol J, Morrissey D, ElAndaloussi S, Wood MJ, Meisner-Kober N.  Journal of Cell Biology 2016, Apr 25;213(2):173-84.

• Ultrafiltration with size-exclusion liquid chromatography for high yield isolation of extracellular vesicles preserving intact biophysical and functional properties. Nordin JZ, Lee Y, Vader P, Mäger I, Johansson HJ, Heusermann W, Wiklander OP, Hällbrink M, Seow Y, Bultema JJ, Gilthorpe J, Davies T, Fairchild PJ, Gabrielsson S, Meisner-Kober NC, Lehtiö J, Smith CI, Wood MJ, El Andaloussi S. Nanomedicine. 2015 May;11(4):879-83.

• Highly complementary target RNAs promote release of guide RNAs from human Argonaute2. De N, Young L, Lau PW, Meisner-Kober N, Morrissey D, MacRae I. Mol Cell (2013), May 9;50(3):344-55.

• The rough endoplasmatic reticulum is a central nucleation site of siRNA-mediated RNA silencing. Stalder L, HeusermannW, Sokol L, Trojer D, Wirz J, Hean J, Fritzsche A, Aeschimann F, Pfanzagl V, Basselet P, Weiler J, Hintersteiner M, Morrissey DV, Meisner-Kober NC. EMBO J (2013); Apr 17;32(8):1115-27.

• Terminal Adenosyl Transferase activity of posttranscriptional regulator HuR revealed by confocal on-bead screening. Meisner NC, Hintersteiner M, Seifert JM, Bauer R, Benoit RM, Widmer A, Schindler T, Uhl V, Lang M, Gstach H, Auer M. (2009)Journal of Molecular Biology, 2009, 3(8), p.435-50.

• Identification and mechanistic characterization of low molecular weight inhibitors for HuR. Meisner NC, Hintersteiner M, Mueller K, Bauer R, Seifert JS, Naegeli HU, Ottl J, Oberer L, Guenat C, Moss S, Harrer N, Woisetschlager M, Buehler C, Uhl V, Auer M. Nature Chemical Biology, 2007, Aug;3(8):508-15.