List of Publications Osteocyte numbers decrease only in postcranial but not in cranial bones in humans of advanced age.  Stigler RG, Becker K, Hasanov E, Hörmann R, Gassner R, Lepperdinger G. Ann Anat. 2019 Nov;226:57-63. doi: 10.1016/j.aanat.2019.06.006. Epub 2019 Jul 19. PMID: 31330307. Hard Tissue Augmentation of Aged Bone by Means of a Tin-Free PLLA-PCL Co-Poylmer Exhibiting in vivo Anergy and Long-Term Structural Stability. Schimke MM, Paul S, Tillmann K, Lepperdinger G, Sigler RG. Geronotology. 2019;65(2): 174-185.doi: 10.1159/000494798.Epub 2019 Jan 24. PMID: 30677770. Pervasion of beta-tricalcium phosphate with nanodiamond particles yields efficient and safe bone replacement material amenable for biofunctionalization and application in large-size osseous defect healing. Stigler RG, Schimke MM, Bigus S, Steinmüller-Nethl D, Tillmann K, Lepperdinger G. Nanomedicine. 2019 Feb;16:250-257. doi: 10.1016/j.nano.2018.08.015.Epub 2018 Sep 26.PMID: 30267872. Long-lived murine osteocytes are embodied by craniofacial skeleton in young and old animals whereas they decrease in number in postcranial skeletons at older ages. Stigler RG, Becker K, Kloss FR, Gassner R, Lepperdinger G. Gerodontology. 2018 Dec;35(4):391-397. doi: 10.1111/ger.12362. Epub 2018 Jul 27. PMID: 30052290. A domestic porcine model for studying the effects of radiation on head and neck cancers. Arnold CR, Kloss F, Singh S, Vasiljevic D, Stigler R, Auberger T, Wenzel V, Klima G, Lukas P, Lepperdinger G, Gassner R. Oral Surg Oral Med Oral Pathol Oral Radiol. 2017 May;123(5):536-543.doi:10.1016/j.oooo.2016.11.017.Epup 2016 Dec 7. PMID: 28130028 Frailty in mouse ageing: A conceptual approach. von Zglinicki T, Varela Nieto I, Brites D, Karagianni N, Ortolano S, Georgopoulos S, Cardoso AL, Novella S, Lepperdinger G, Trendelenburg AU, van Os R. Mech Ageing Dev. 2016 Dec; 160:34-40. doi: 10.1016/j.mad.2016.07.004. Epup 2016 Jul 18. Review. PMID: 27443148. mir-24 activity progagates stress-induced senescence by down regulating DNA topoisomerase 1. Bu H, Lepperdinger G, Jansen-Dürr P. Exp Gerontol. 206 Mar; 75:48-52.doi: 10.1016/j.exger.2015.012. Epub 2015 Dec 31. PMID: 26748253. 2016 Apr;12(3):823-33. doi: 10.1016/j.nano.2015.11.004. Epub 2015 Dec 3.PMID: 26654993 Biofunctionalization of scaffold material with nano-scaled diamond particles physisorbed with angiogenic factors enhances vessel growth after implantation. Schimke MM, Stigler R, Wu X, Waag T, Buschmann P, Kern J, Untergasser G, Rasse M, Steinmüller-Nethl D, Krueger A, Lepperdinger G.Nanomedicine. Front Physiol. 2015 Dec 2;6:362. doi: 10.3389/fphys.2015.00362. eCollection 2015. PMID: 26696897 Review. Patient-Specific Age: The Other Side of the Coin in Advanced Mesenchymal Stem Cell Therapy. Schimke MM, Marozin S, Lepperdinger G. Transfus Apher Sci. 2015 Apr 8. pii: S1473-0502(15)00072-5. doi: 10.1016/j.transci.2015.04.008. [Epub ahead of print] Systemic impact molds mesenchymal stromal/stem cell aging. Reitinger S1, Schimke M1, Klepsch S1, de Sneeuw S1, Yani SL1, Gaßner R2, Ertl P3, Lepperdinger G4. Trends Biotechnol. 2014 May;32(5):245-53. doi: 10.1016/j.tibtech.2014.03.004. Epub 2014 Apr 9. Lab-on-a-chip technologies for stem cell analysis. Ertl P1, Sticker D2, Charwat V3, Kasper C3, Lepperdinger G4. Methods Mol Biol. 2013;976:99-109. doi: 10.1007/978-1-62703-317-6_8. Isolation of mesenchymal stem cells from human bone and long-term cultivation under physiologic oxygen conditions. Klepsch S1, Jamnig A, Trimmel D, Schimke M, Kapferer W, Brunauer R, Singh S, Reitinger S, Lepperdinger G. Gerontology. 2013;59(1):71-6. doi: 10.1159/000342200. Epub 2012 Sep 22. Hyaluronan, a ready choice to fuel regeneration: a mini-review. Reitinger S1, Lepperdinger G. Exp Gerontol. 2013 Jul;48(7):644-6. doi: 10.1016/j.exger.2012.07.004. Epub 2012 Jul 20. Developmental programs are kept alive during adulthood by stem cells: the aging aspect. Lepperdinger G1. Electric impedance sensing in cell-substrates for rapid and selective multipotential differentiation capacity monitoring of human mesenchymal stem cells. Reitinger S, Wissenwasser J, Kapferer W, Heer R, Lepperdinger G. Biosens Bioelectron. 2012 Apr 15;34(1):63-9. doi: 10.1016/j.bios.2012.01.013. Epub 2012 Feb 8. Mesenchymal stem cells show radioresistance in vivo. Singh S, Kloss FR, Brunauer R, Schimke M, Jamnig A, Greiderer-Kleinlercher B, Klima G, Rentenberger J, Auberger T, Hächl O, Rasse M, Gassner R, Lepperdinger G. J Cell Mol Med. 2012 Apr;16(4):877-87. doi: 10.1111/j.1582-4934.2011.01383.x. Inflammation and mesenchymal stem cell aging. Lepperdinger G. Curr Opin Immunol. 2011 Aug;23(4):518-24. doi: 10.1016/j.coi.2011.05.007. Epub 2011 Jun 22. Review.